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Is there an inverted U-shaped curve?Empirical analysis of the Environmental Kuznets Curve in agrochemicals

Fei LI,Suocheng DONG,Fujia LI,Libiao YANG

《环境科学与工程前沿（英文）》 2016年第10卷第2期页码 276-287 doi: 10.1007/s11783-014-0700-y

摘要： As the largest contributor to water impairment, agriculture-related pollution has attracted the attention of scientists as well as policy makers, and quantitative information is being sought to focus and advance the policy debate. This study applies the panel unit root, heterogeneous panel cointegration, and panel-based dynamic ordinary least squares to investigate the Environmental Kuznets Curve on environmental issues resulting from use of agricultural synthetic fertilizer, pesticide, and film for 31 provincial economies in mainland China from 1989 to 2009. The empirical results indicate a positive long-run co-integrated relationship between the environmental index and real GDP per capita. This relationship takes on the inverted U-shaped Environmental Kuznets Curve, and the value of the turning point is approximately 10,000–13,000, 85,000–89,000 and over 160,000 CNY, for synthetic fertilizer nitrogen indicator, fertilizer phosphorus indicator and pesticide indicator, respectively. At present, China is subject to tremendous environmental pressure and should assign more importance to special agriculture-related environmental issues.

关键词： Environmental Kuznets Curve agrochemical China

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Analytical solutions of three-dimensional contaminant transport in uniform flow field in porous media: A library

Hongtao WANG, Huayong WU

《环境科学与工程前沿（英文）》 2009年第3卷第1期页码 112-128 doi: 10.1007/s11783-008-0067-z

摘要： The purpose of this study is to present a library of analytical solutions for the three-dimensional contaminant transport in uniform flow field in porous media with the first-order decay, linear sorption, and zero-order production. The library is constructed using Green's function method (GFM) in combination with available solutions. The library covers a wide range of solutions for various conditions. The aquifer can be vertically finite, semi-infinitive or infinitive, and laterally semi-infinitive or infinitive. The geometry of the sources can be of point, line, plane or volumetric body; and the source release can be continuous, instantaneous, or by following a given function over time. Dimensionless forms of the solutions are also proposed. A computer code FlowCAS is developed to calculate the solutions. Calculated results demonstrate the correctness of the presented solutions. The library is widely applicable to solve contaminant transport problems of one- or multiple- dimensions in uniform flow fields.

关键词： solution library contaminant transport analytical solution dispersion and advection porous media type curve Green's function method (GFM)

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Learning curve of totally thoracoscopic pulmonary segmentectomy

Weibing Wu, Jing Xu, Wei Wen, Yue Yu, Xinfeng Xu, Quan Zhu, Liang Chen

《医学前沿（英文）》 2018年第12卷第5期页码 586-592 doi: 10.1007/s11684-017-0566-z

摘要：

Totally thoracoscopic pulmonary segmentectomy (TTPS) is a feasible and safe technique that requires advanced thoracoscopic skills and knowledge of pulmonary anatomy. However, data describing the learning curve of TTPS have yet to be obtained. In this study, 128 patients who underwent TTPS between September 2010 and December 2013 were retrospectively analyzed to evaluate the learning curve and were divided chronologically into three phases, namely, ascending phase (A), plateau phase (B), and descending phase (C), through cumulative summation (CUSUM) for operative time (OT). Phases A, B, and C comprised 39, 33, and 56 cases, respectively. OT and blood loss decreased significantly from phases A to C (P <0.01), and the frequency of intraoperative bronchoscopy for target bronchus identification decreased gradually (A, 8/39; B, 4/33; C, 3/56; P = 0.06). No significant differences were observed in demographic factors, conversion, complications, hospital stay, and retrieved lymph nodes among the three phases. Surgical outcomes and techniques improved with experience and volume. CUSUM_OT indicated that the learning curve of TTPS should be more than 72 cases.

关键词： thoracoscopic segmentectomy learning curve CUSUM

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Numerical investigation of circle defining curve for two-dimensional problem with general boundaries

Chung Nguyen VAN

《结构与土木工程前沿（英文）》 2019年第13卷第1期页码 92-102 doi: 10.1007/s11709-018-0472-8

摘要： The scaled boundary finite element method (SBFEM) is applied to the static analysis of two dimensional elasticity problem, boundary value problems domain with the domain completely described by a circular defining curve. The scaled boundary finite element equations is formulated within a general framework integrating the influence of the distributed body force, general boundary conditions, and bounded and unbounded domain. This paper investigates the possibility of using exact geometry to form the exact description of the circular defining curve and the standard finite element shape function to approximate the defining curve. Three linear elasticity problems are presented to verify the proposed method with the analytical solution. Numerical examples show the accuracy and efficiency of the proposed method, and the performance is found to be better than using standard linear element for the approximation defining curve on the scaled boundary method.

关键词： exact geometry circular defining curve general boundaries SBFEM

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New practice in semaglutide on type-2 diabetes and obesity: clinical evidence and expectation

《医学前沿（英文）》 2022年第16卷第1期页码 17-24 doi: 10.1007/s11684-021-0873-2

摘要： Obesity is an important risk factor of type 2 diabetes (T2D), which has become an important factor threatening human health. However, no perfect drug choice for obesity exists. Semaglutide is a kind of human glucagon-like peptide-1 (GLP-1) analog that promotes insulin secretion while inhibiting glucagon secretion through a glucose concentration-dependent mechanism. GLP-1 can also delay stomach emptying and suppress appetite to help lose weight. This review summarizes clinical evidence of the semaglutide effect on T2D and obesity and establishes expectations on future clinical trials for obesity treatment.

关键词： semaglutide type 2 diabetes obesity

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学习曲线及在工业生产运作研究中的应用综述

陈志祥

《中国工程科学》 2007年第9卷第7期页码 82-88

摘要：

学习曲线是一种通过生产者行为学习与经验积累而得到改进的生产产出的特征函数，利用学习曲线可以科学地制定成本计划，改善作业计划、劳动定额与劳力规划，质量改善等。对国际上的研究文献、学习曲线的表现形式及其特点进行分析，探讨了几个新的应用动向。

关键词：学习曲线运作管理行为研究

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Research on physical shape preserving curve reconstruction

TANG Kelun, ZHANG Xiangwei, CHENG Siyuan, XIONG Hanwei, ZHANG Hong

《机械工程前沿（英文）》 2007年第2卷第3期页码 305-309 doi: 10.1007/s11465-007-0054-2

摘要： Fusion of various data is an effective way to improve the precision and efficiency of acquiring information in reverse engineering. A method of physical shape preserving curve reconstruction is proposed to better realize the data fusion of coordinate measuring machine (CMM) and visual information. From the principle of materials mechanics, the strain energy of the curve corresponding to the distortion is advanced as the internal energy, and the elastic potential energy of the curve is established, using a few precise measured data points as the equilibrium position, to be the external energy. On the basis of the principle of variation calculus, the basic spline finite element method (B-spline FEM) is used to determine the equilibrium position of curve deformation. Numerical simulation indicates that there is an extremely good agreement between the new fitted curve and the actual curve.

关键词： information CMM Numerical simulation effective coordinate measuring

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Interpolation of a spline developable surface between a curve and two rulings

Alicia CANTÓN,Leonardo FERNÁNDEZ-JAMBRINA

《信息与电子工程前沿（英文）》 2015年第16卷第3期页码 173-190 doi: 10.1631/FITEE.14a0210

摘要： In this paper we address the problem of interpolating a spline developable patch bounded by a given spline curve and the first and the last rulings of the developable surface. To complete the boundary of the patch, a second spline curve is to be given. Up to now this interpolation problem could be solved, but without the possibility of choosing both endpoints for the rulings. We circumvent such difficulty by resorting to degree elevation of the developable surface. This is useful for solving not only this problem, but also other problems dealing with triangular developable patches.

关键词： Developable surfaces Spline surfaces Blossoms

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Principle and curve of planetary indexing cam mechanisms

LIU Ming-tao, ZHANG Ce, YANG Yu-hu

《机械工程前沿（英文）》 2006年第1卷第4期页码 475-478 doi: 10.1007/s11465-006-0063-6

摘要： A new type of planetary indexing cam mechanism called type !c is presented. The transmission principle of type !c is discussed. Based on the principle of formation of conjugate tooth contour, the equations of the cam s pitch curve are derived. The continuity and symmetry of the cam s pitch curve are also analyzed. It can be concluded that: 1) This type has no output institution so the output precision can be improved; 2) The asymmetrical two-ring structure is used to overcome dead point and its phase angle is equal to (π - 2π/n); 3) The continuous condition of the cam s pitch curve is that the average transmission ratio is -n in an intermittent motion period.

关键词： continuity planetary average transmission symmetry intermittent

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Personalized medicine of type 2 diabetes

null

《医学前沿（英文）》 2013年第7卷第1期页码 1-3 doi: 10.1007/s11684-013-0241-y

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Detection of void and metallic inclusion in 2D piezoelectric cantilever beam using impedance measurements

S. SAMANTA, S. S. NANTHAKUMAR, R. K. ANNABATTULA, X. ZHUANG

《结构与土木工程前沿（英文）》 2019年第13卷第3期页码 542-556 doi: 10.1007/s11709-018-0496-0

摘要： The aim of current work is to improve the existing inverse methodology of void-detection based on a target impedance curve, leading to quick-prediction of the parameters of single circular void. In this work, mode-shape dependent shifting phenomenon of peaks of impedance curve with change in void location has been analyzed. A number of initial guesses followed by an iterative optimization algorithm based on univariate method has been used to solve the problem. In each iteration starting from each initial guess, the difference between the computationally obtained impedance curve and the target impedance curve has been reduced. This methodology has been extended to detect single circular metallic inclusion in 2D piezoelectric cantilever beam. A good accuracy level was observed for detection of flaw radius and flaw-location along beam-length, but not the precise location along beam-width.

关键词： piezoelectricity impedance curve mode shapes inverse problem flaw detection curve shifting

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Immunological and virological characteristics of human immunodeficiency virus type 1 superinfection:

null

《医学前沿（英文）》 2017年第11卷第4期页码 480-489 doi: 10.1007/s11684-017-0594-8

摘要：

Superinfection is frequently detected among individuals infected by human immunodeficiency virus type I (HIV-1). Superinfection occurs at similar frequencies at acute and chronic infection stages but less frequently than primary infection. This observation indicates that the immune responses elicited by natural HIV-1 infection may play a role in curb of superinfection; however, these responses are not sufficiently strong to completely prevent superinfection. Thus, a successful HIV-1 vaccine likely needs to induce more potent and broader immune responses than those elicited by primary infection. On the other hand, potent and broad neutralization responses are more often detected after superinfection than during monoinfection. This suggests that broadly neutralizing antibodies are more likely induced by sequential immunization of multiple different immunogens than with only one form of envelope glycoprotein immunogens. Understanding why the protection from superinfection by immunity induced by primary infection is insufficient and if superinfection can lead to cross-reactive immune responses will be highly informative for HIV-1 vaccine design.

关键词： human immunodeficiency virus type I superinfection incidence immune response

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Metabolomics in human type 2 diabetes research

null

《医学前沿（英文）》 2013年第7卷第1期页码 4-13 doi: 10.1007/s11684-013-0248-4

摘要：

The high prevalence of diabetes and diabetic complications has caused a huge burden on the modern society. Although scientific advances have led to effective strategies for preventing and treating diabetes over the past several decades, little progress has been made toward curing the disease or even getting it under control, from a public health and overall societal standpoint. There is still a lack of reliable biomarkers indicative of metabolic alterations associated with diabetes and different drug responses, highlighting the need for the development of early diagnostic and prognostic markers for diabetes and diabetic complications. The emergence of metabolomics has allowed researchers to systemically measure the small molecule metabolites, which are sensitive to the changes of both environmental and genetic factors and therefore, could be regarded as the link between genotypes and phenotypes. During the last decade, the progression made in metabolomics has provided insightful information on disease development and disease onset prediction. Recent studies using metabolomics approach coupled with statistical tools to predict incident diabetes revealed a number of metabolites that are significantly altered, including branched-chain and aromatic amino acids, such as isoleucine, leucine, valine, tyrosine and phenylalanine, as diagnostic or highly-significant predictors of future diabetes. This review summarizes the current findings of metabolomic studies in human investigations with the most common form of diabetes, type 2 diabetes.

关键词： metabolomics type 2 diabetes metabolic pathway mass spectrometry nuclear magnetic resonance (NMR)

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交换式以太网NC建模与实时性能分析

王晓欣,刘鲁源,刘昆,马津艳

《中国工程科学》 2006年第8卷第6期页码 55-59

摘要：

交换式以太网的实时性能分析是工业以太网研究领域的一个热点课题，目前还没有一个有效的数学模型来对其进行描述。通过对典型交换机结构的分析，应用网络微积分理论建立了交换机的服务曲线模型，该模型将交换机中的数据流分为实时数据和非实时数据，并得到了最大延迟值和最大缓存需求值等，最大延迟为交换机的实时应用提供了理论边界值，最大缓存需求值为在实时工业环境中的交换机构建提供了理论参考。

关键词：网络微积分交换机到达曲线服务曲线延迟